Cst foxo3a

Web(12829) FoxO3a (D19A7) Rabbit mAb - Cell Signaling Technology - CiteAb 194 citations – A rabbit monoclonal antibody, raised against Forkhead box protein O3 (Human), supplied … Web56484 Ensembl ENSG00000118689 ENSMUSG00000048756 UniProt O43524 Q9WVH4 RefSeq (mRNA) NM_001455 NM_201559 NM_019740 NM_001376967 RefSeq (protein) NP_001446 NP_963853 NP_062714 NP_001363896 Location (UCSC) Chr 6: 108.56 – 108.68 Mb Chr 10: 42.06 – 42.15 Mb PubMed search Wikidata View/Edit Human …

A型核纤层蛋白编码基因LMNA调控IOP1表达机制的初步研究*

WebMay 21, 2024 · Silencing of PTEN by transfection with siPTEN activated the PI3K/Akt/mTOR signaling pathway in lung cancer cells, as indicated by significantly increased phosphorylation of Akt, FoxO3a, and mTOR (P < 0.05, < 0.01, and < 0.005) . These results suggested that the PI3K/Akt/mTOR pathway was activated by PTEN silencing and … WebJun 28, 2024 · The following primary antibodies were used: Ubiquitin (#3933; Cell Signaling Technology (CST) Japan, Tokyo, Japan), p-Forkhead box O (FOXO) 1 Ser256 (#84192; CST), FOXO1 (#2880; CST), p-FOXO3a Ser253 (#9466; CST), FOXO3a (#2497; CST), LC3 (#2775; CST), p62/SQSTM (PM045, Medical & Biological Laboratory, Nagoya, Japan), p … north bergen post office 79th https://charlotteosteo.com

Resveratrol attenuates radiation enteritis through the SIRT1/FOXO3a …

WebForkhead box O (FOXO) proteins are a family of transcription factors with four members in mammals, namely FOXO1, FOXO3a, FOXO4, and FOXO6. FOXO factors, originally … WebDec 1, 2016 · For example, FoxO3a activates FasL transcription, the ligand for the Fas-dependent cell death pathway or pro-apoptotic Bim gene and initiates apoptosis. FoxO3a also induces the expression of cell cycle progression inhibitors including p27 and CyclinD1, thus stalling the G1/S phase transition . Here, we investigated whether the survival … WebFOXO3a were positively correlated, and both were associated with longer sur-vival in lung cancer patients. Conclusion: Overall, the present study is the first to show that Adjudin syner-gizes with paclitaxel and inhibits cell growth and metastasis by regulating the SIRT3–FOXO3a axis in SCLC; thus, Adjudin has great potential to be an anti- how to replace sway bar links prado 90 series

The FOXO3-FOXM1 axis: A key cancer drug target and a …

Category:FoxO3a Antibody Cell Signaling Technology

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Cst foxo3a

The FOXO3-FOXM1 axis: A key cancer drug target and a …

WebMonoclonal Antibody for studying FoxO3a. Cited in 187 publications. Validated for WB, IP, IHC, IF, F. Highly specific and rigorously validated in-house, FoxO3a (D19A7) Rabbit Monoclonal Antibody (CST #12829) is …

Cst foxo3a

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WebMar 1, 2024 · Chitosan targets PI3K/Akt/FoxO3a axis to up-regulate FAM172A and suppress MAPK/ERK pathway to exert anti-tumor effect in osteosarcoma - ScienceDirect Chemico-Biological Interactions Available online 25 January 2024, 110354 In Press, Journal Pre-proof Research paper WebThe FOXO3 and FOXM1 forkhead box transcription factors, functioning downstream of the essential PI3K-Akt, Ras-ERK and JNK/p38MAPK signalling cascades, are crucial for cell proliferation, differentiation, cell survival, senescence, DNA …

WebFoxO3a (75D8) Rabbit mAb detects exogenous and endogenous levels of total FoxO3a protein. The antibody does not detect the exogenously expressed family members FoxO4 or FoxO1. Species Reactivity: Human, Mouse, Rat, Monkey Source / Purification WebSep 25, 2024 · The protein stability of FOXO3A is regulated by Casein Kinase 1 alpha (CK1α) in an oncogenic RAS-specific manner, but whether this mode of regulation extends to related FOXO family members is ...

WebIOP1抗体、Lamin A/C抗体、LC3BⅠ抗体、LC3BⅡ抗体、FOXO3a抗体、p62抗体、ATG5、ATG12抗体、GAPDH抗体均购自美国CST公司。荧光定量PCR仪型号为LightCycler 480，购自瑞士罗氏公司。 1.2方法. 1.2.1细胞培养 HEK293T在37 ℃，5% CO2培养箱中用含10% FBS的高糖DMEM培养基培养。 WebOct 15, 2024 · Previously, FoxO3a has been found to modulate autophagy through inducing expression of several autophagy-related genes, including LC3, Beclin-1, and P62 [5, 33]. Inhibition of FoxO3a exhibited effects of neuroprotection following TBI and induction of TBI was found to translocate cytosolic FoxO3a into nucleus [ 33 ].

WebNov 1, 2024 · Results. Exercise can significantly attenuate AngⅡ-induced muscle atrophy, which is demonstrated by increased skeletal muscle weight, cross-sectional area of myofiber, and activation of AKT/mTOR signaling and by decreased atrogenes expressions and apoptosis. In AngⅡ-induced muscle atrophy mice models, PPARγ was elevated …

WebFeb 18, 2024 · Previous evidence showed that the SIRT3–FOXO3a axis was a tumor suppressor in many cancers 42-44 it influenced EMT, 45 proliferation 46 and apoptosis. 47 Here, we confirmed that Adjudin activated the SIRT3–FOXO3a axis in SCLC, and the anticancer effect of Adjudin can be influenced by the expression levels of SIRT3 and … how to replace switch charging portWebJul 16, 2024 · The differential expressions of IGF-1R, FOXO3A, and BIM in the benign versus malignant prostate tissues supported a negative association between the FOXO3A/BIM axis and IGF-1R expression in human ... north bergen presbyterian churchWebApr 22, 2024 · FOXO3a is a key target of AKT, and AKT phosphorylates FOXO3a at Thr32 residues, resulting in a decreased expression of FOXO3a. We then investigated whether … how to replace swiffer duster headWeb豆丁网是面向全球的中文社会化阅读分享平台，拥有商业,教育,研究报告,行业资料,学术论文,认证考试,星座,心理学等数亿实用 ... north bergen property taxesWebJul 25, 2024 · FOXO3a is widely implicated in a variety of diseases, particularly in malignancy of breast, liver, colon, prostate, bladder, and nasopharyngeal cancers. … north bergen property tax payment onlineWeb(12829) FoxO3a (D19A7) Rabbit mAb Sign in or register to save this reagent to your favourites Supplier Cell Signaling Technology Host Rabbit Type Primary Clonality Recombinant (D19A7F3) Recombinant Yes Conjugate Unconjugated Target Forkhead box protein O3 (Human) UniProt O43524 - FOXO3_HUMAN Gene FOXO3 Modification … how to replace sway bar link dodge ram 1500WebJan 1, 2012 · Doxorubicn treatment induces p38 MAPK activity and FOXO3a nuclear accumulation in MCF-7 breast carcinoma cell line. A, MCF-7 cells were treated with 1 μmol/liter of doxorubicin for 0, 1, 2, 4, 8, 16, and 24 h. At the indicated time, the cells were collected and analyzed by Western blotting using the antibodies indicated. north bergen real estate attorney