Destruction of articular cartilage
WebJun 25, 2016 · Hyaluronic acid (HA) is used clinically to treat osteoarthritis (OA), but its pharmacological effects under hypoxic conditions remain unclear. Articular chondrocytes in patients with OA are exposed to a hypoxic environment. This study investigated whether hypoxia could potentiate the anabolic effects of exogenous HA in rat articular cartilage … WebJul 26, 2024 · One of the primary causes of articular cartilage damage is injury to the joints, especially the knee joint and hip joint. Injuries, especially if they are not treated properly, can accelerate natural …
Destruction of articular cartilage
Did you know?
WebMar 23, 2016 · These articular cartilage injuries, ... In conclusion, our results collectively indicate that miR-365 acts as a mechanically induced mediator of osteoarthritic cartilage destruction, by directly regulating HDAC4. Mechanical overload is an important risk factor in OA pathogenesis. Furthermore, in the late stage of OA, stress from the combination ... Web"Articular cartilage damage is caused by both acute and repetitive trauma resulting in knee pain, effusion or mechanical symptoms," explains Michael J. Stuart, M.D., orthopedic …
WebArticular cartilage repair treatment is focused on the restoration of the surface of an articular joint 's hyaline cartilage. Over the last few decades, surgeons and researchers …
WebMar 22, 2024 · When the articular cartilage is damaged, surgical procedures can effectively repair and restore the tissue. In general, … WebOct 17, 2016 · Injured, inflamed, or damaged cartilage can cause symptoms such as pain and limited movement. It can also lead to joint damage and deformity. Causes of …
WebAnd articular cartilage, like all cartilage, is avascular, meaning it lacks any sort of vasculature or blood vessels. And so, it has a hard time getting the nutrients it needs to heal and recover if it were to become damaged by overuse or infection. ... And this can lead to permanent destruction of articular cartilage, which causes the pain and ...
WebDec 5, 2024 · The articular cartilage is a type of specialized connective tissue present in synovial joints. It is composed of hyaline cartilage with a dense extracellular matrix and … shubh trade indiabullsWebOct 30, 2015 · Osteoarthritis (OA), the most common chronic joint disease in the elderly population, is characterized by progressive destruction of articular cartilage, resulting in significant disability. Because articular cartilage depends solely on its resident cells, the chondrocytes, for the maintenance of extracellular matrix, the compromising of ... shubhtithi weddingsWebJul 18, 2013 · Rheumatoid arthritis (RA) is the most common inflammatory arthropathy worldwide. It is a chronic, complex, and heterogeneous autoimmune disease (AD). It is characterized by the presence of long … shubh trading companyWebOn the contrary, HIF-2α is mainly involved in inducing the expression of catabolic factors in chondrocytes, enhancing the expression of Fas, promoting the apoptosis of … theo taylorWebArticular cartilage injuries can occur as a result of either traumatic mechanical destruction or progressive mechanical degeneration (wear and tear). Mechanical destruction of … shubh trade indiabulls loginWebThe pathogenesis of osteoarthritis involves multiple etiologies, including mechanical, biochemical, and genetic factors that contribute to the imbalance in the synthesis and … shubh ultrasoundWebThroughout life, articular cartilage undergoes internal remodeling as the cells replace matrix macromolecules lost through degradation. Aging decreases the ability of … shubh time today sydney