High affinity copper uptake protein

WebCatalog FieldsAntigen: High affinity copper uptake protein 1Available to For-Profits: YesAntigen Species: HumanHybridoma Cells Available (Non-Profit): NoIsotype: MIgG2bDepositor: Clinical Proteomics Technologies for CancerHost Species: mouseAntigen Sequence: Positive Tested Species Reactivity: HumanDepositors Institution: National … High affinity copper uptake protein 1 (CTR1) is a protein that in humans is encoded by the SLC31A1 gene. Copper is an element essential for life, but excessive copper can be toxic or even lethal to the cell. Therefore, cells have developed sophisticated ways to maintain a critical copper balance, with the intake, export, … Ver mais In 2024, a new autosomal-recessive disease was discovered that is caused by mutations of the CTR1 gene. The disease is characterized by profound deficiency of copper in the central nervous system and presents with … Ver mais • Solute carrier family Ver mais • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". … Ver mais

Molecular Characterization of hCTR1, the Human Copper Uptake Protein ...

Web5 de jan. de 2024 · high affinity copper uptake protein 1, copper transporter 1, solute carrier family 13 (sodium/sulphate symporters), member 1 GeneRIFs: Gene … WebChimera protein of High affinity copper uptake protein 1 and Soluble cytochrome b562HEXATANTALUM DODECABROMIDEZINC ION. NCBI. National Center for Biotechnology Information. Search. 6M97: Crystal structure of the high-affinity copper transporter Ctr1. PDB ID: 6M97 Download: MMDB ID: 173912: PDB Deposition Date: sharad rao politician https://charlotteosteo.com

The copper transporter CTR1 provides an essential function in

Web5 de abr. de 2024 · Ctr1, a high-affinity copper transporter, is a homotrimeric integral membrane protein that provides the main route for cellular copper uptake. Together with … WebIt was shown that a gene, CTR1, encoded a multispanning plasma membrane protein that was specifically required for high affinity copper transport into yeast.The CTR1 gene product is a protein composed of 406 amino acid residues. A second high affinity copper uptake protein, encoded by the CTR3 gene, was subsequently identified. The two gene … WebHigh affinity copper uptake protein 1 DrugBank Online with DrugBank on your side. High affinity copper uptake protein 1 Details Name High affinity copper uptake protein 1 Synonyms Copper transporter 1 COPT1 CTR1 hCTR1 Solute carrier family 31 member 1 Gene Name SLC31A1 Organism Humans Amino acid sequence sharad purnima 2020 in hindi

UniProt

Category:SLC31A1 Antibody (CPTC-SLC31A1-1) - DSHB

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High affinity copper uptake protein

The SLC31 (Ctr) copper transporter family - PubMed

WebThe redox active metal copper is an essential cofactor in critical biological processes such as respiration, iron transport, oxidative stress protection, hormone production, and pigmentation. A widely conserved family of high affinity copper transport proteins (Ctr proteins) mediates copper uptake at the plasma membrane. However, little is known … Web8 de abr. de 2024 · HIGHLIGHTS. who: Nina Salustros from the (UNIVERSITY) have published the research: Structural basis of ion uptake in copper-transporting P1B-type ATPases, in the Journal: (JOURNAL) of 16/08/2024 what: Transport and regulation mechanism Based on detailed analyses of the structurally determined E1 state and …

High affinity copper uptake protein

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Web5 de jun. de 2001 · Previously, we described a human gene (CTR1;SLC31A1) that encodes a high-affinity copper-uptake protein and hypothesized that this protein is required for … WebBecause copper uptake at the cell membrane is a crucial step in copper acquisition, yeast genes encoding the high affinity copper transport proteins are tightly regulated in response to copper levels to ensure that …

Web30 de mar. de 2024 · Functional assays revealed that it stimulates the initial rate of radiolabeled copper uptake. CTR1 transports copper with high affinity in a time-dependent and saturable manner and is copper-specific. Transport is an energy-independent process and is stimulated by extracellular acidic pH and high K+ … WebThe major human high-affinity copper uptake protein, human copper transporter hCTR1, was recently shown to be at the basolateral or blood side of both intestinal and renal ...

Web12 de abr. de 2024 · To overcome this challenge, bacteria synthesize high-affinity iron-binding molecules called siderophores, which are recognized by specific transporters on … WebHigh affinity copper uptake protein 1 Alternative names Copper transporter 1 ( rCTR1) Liver regeneration-related protein LRRGT00200 Solute carrier family 31 member 1 …

Web15 de mar. de 1996 · Two proteins in the plasma membrane of yeast—a multicopper oxidase, encoded by the FET3 gene, and a permease, encoded by the FTR1 gene—were shown to mediate high-affinity iron uptake. FET3 expression was required for FTR1 protein to be transported to the plasma membrane.

Web11 de abr. de 2024 · To investigate whether Met44 residue in COPT1 is also sufficient for copper acquisition, we converted Met44 to alanine in the full-length COPT1 protein, and transformed this mutant allele [COPT1(M44A)] into S. cerevisiae ctr1Δctr3Δ strain which lacks high affinity copper transporters CTR1 and CTR3 and cannot grow on … shara d productionsWebHuman CTR1 is a high-affinity copper transporter that also mediates the uptake of the anticancer drug cisplatin by largely unknown transport mechanisms. Here we report the 6 … pool change color peeWebGene ID: 102804936, updated on 5-Feb-2024. Summary Other designations. high affinity copper uptake protein 1-like pool changeWebProtein High affinity copper uptake protein 1 Gene SLC31A1 Status UniProtKB reviewed (Swiss-Prot) Organism Homo sapiens (Human) Amino acids 190 Protein existence … shara dream schoolWeb16 de mar. de 2010 · Copper and iron are essential elements employed in pathways that are conserved in all kingdoms of life. In eukaryotes, several interdependent connections between copper and iron homeostasis have been described previously ().For example, high-affinity iron uptake in Saccharomyces cerevisiae is mediated by multicopper … sharad rathodWebCopper (Cu) is an essential trace element for growth and development and abnormal Cu levels are associated with anemia, metabolic disease and cancer. Evolutionarily … sharad purnima in englishWebAlternate Antibody Name: Alternate Gene Names: Solute Carrier Family 31 (Copper Transporter), Member 1; COPT1; CTR1; Copper Transporter 1; Solute Carrier Family 31 … pool change house